This is the first article in a series of four, describing the characterization of protein-based bio-therapeutics by bottom-up analysis at peptide level (Peptide Mapping Analysis). This article ...

Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceuticals, including protein-based therapies, require extensive characterization, ...

Peptide mapping for biotherapeutic proteins relies on protein digestion which includes the enzymatic treatment of a protein to produce peptide fragments to further characterize specific peptide ...